Mus musculus Protein: Prss41
Summary
InnateDB Protein IDBP-533879.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prss41
Protein Name protease, serine, 41
Synonyms 4931440B09Rik; Tessp-1; Tessp1;
Species Mus musculus
Ensembl Protein ENSMUSP00000122453
InnateDB Gene IDBG-144662 (Prss41)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane {ECO:0000269PubMed:15515062, ECO:0000269PubMed:19798924}; Lipid-anchor, GPI-anchor {ECO:0000269PubMed:15515062, ECO:0000269PubMed:19798924}. Note=Localized in the plasma membrane of spermatogonia. Localized in intracellular compartment in spermatocytes, probably in the Golgi apparatus.
Disease Associations
Tissue Specificity Testis-specific. Expressed in spermatogonia and spermatocytes. Expressed in Leydig and Sertoli cells (at protein level). Expressed 2 weeks after birth and remains highly expressed in the sexually mature testis. Expressed in the seminiferous tubules but not in the interstitial tissues. Expressed in type B spermatogonia and spermatocytes at stages between preleptotene and pachytene during the spermatogenesis cycle. {ECO:0000269PubMed:15515062, ECO:0000269PubMed:19798924}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
GO:0043229 intracellular organelle
Protein Structure and Domains
PDB ID MGI:1918253
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR015420 Peptidase S1A, nudel
PFAM PF00089
PF09342
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q920S2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 71003
UniGene Mm.328839
RefSeq
MGI ID
MGI Symbol Prss41
OMIM
CCDS
HPRD
IMGT
EMBL AB049453 AK049297
GenPept BAB68561 BAC33665