Version 5.4
Mus musculus Protein: 3200002M19Rik
Summary
InnateDB Protein IDBP-534192.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol 3200002M19Rik
Protein Name RIKEN cDNA 3200002M19 gene
Synonyms 3200002M19Rik; 6330414C15Rik; APC15;
Species Mus musculus
Ensembl Protein ENSMUSP00000114771
InnateDB Gene IDBG-202286 (3200002M19Rik)
Protein Structure
UniProt Annotation
Function Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20 (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007067 mitotic nuclear division
GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint
Cellular Component
GO:0005680 anaphase-promoting complex
Protein Structure and Domains
PDB ID MGI:1922680
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P60007
PhosphoSite PhosphoSite-
TrEMBL H3BIU1
UniProt Splice Variant
Entrez Gene 75430
UniGene Mm.284491
RefSeq NP_081808
MGI ID
MGI Symbol Anapc15
OMIM
CCDS CCDS21518
HPRD
IMGT
EMBL AC167240 AK014309 AK135201 AK139635 BC006736 CH466531
GenPept AAH06736 BAB29261 BAE22458 BAE24090 EDL16542

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca