InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tollip

Summary

InnateDB Protein

IDBP-534197.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tollip

Protein Name

toll interacting protein

Synonyms

4930403G24Rik; 4931428G15Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118336

InnateDB Gene

IDBG-212409 (Tollip)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 62 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	62 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005150	interleukin-1, Type I receptor binding
GO:0005515	protein binding
GO:0019900	kinase binding
GO:0031624	ubiquitin conjugating enzyme binding
GO:0031625	ubiquitin protein ligase binding
GO:0032183	SUMO binding
GO:0035325	Toll-like receptor binding

Biological Process

GO:0007165	signal transduction
GO:0016310	phosphorylation
GO:0033235	positive regulation of protein sumoylation

Cellular Component

GO:0016604	nuclear body
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

MGI:1891808

InterPro

IPR000008 C2 domain
IPR003892 Ubiquitin system component Cue
IPR009060 UBA-like

PFAM

PF00168
PF02845

PRINTS

PR00360

PIRSF

SMART

SM00239
SM00546

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A9JEI5

UniProt Splice Variant

Entrez Gene

54473

UniGene

Mm.474076

RefSeq

MGI ID

MGI Symbol

Tollip

OMIM

CCDS

HPRD

IMGT

EMBL

AL772165 CH466531

GenPept

EDL18125