InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Impg2

Summary

InnateDB Protein

IDBP-534330.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Impg2

Protein Name

interphotoreceptor matrix proteoglycan 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000125135

InnateDB Gene

IDBG-167057 (Impg2)

Protein Structure

UniProt Annotation

Function

Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light- sensitive photoreceptor outer segment. Binds heparin.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed in the retina and pineal gland. {ECO:0000269PubMed:12589770}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005540	hyaluronic acid binding
GO:0008201	heparin binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0016021	integral component of membrane
GO:0043235	receptor complex

Protein Structure and Domains

PDB ID

MGI:3044955

InterPro

IPR000082 SEA domain
IPR000742 Epidermal growth factor-like domain

PFAM

PF01390
PF00008

PRINTS

PIRSF

SMART

SM00200
SM00181

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q80XH2

PhosphoSite

PhosphoSite-Q80XH2

TrEMBL

UniProt Splice Variant

Entrez Gene

224224

UniGene

Mm.410026

RefSeq

MGI ID

MGI Symbol

Impg2

OMIM

CCDS

HPRD

IMGT

EMBL

AK047356 AY174061 BC048863

GenPept

AAH48863 AAO21221 BAC33032