Version 5.4
Mus musculus Protein: Capzb
Summary
InnateDB Protein IDBP-534331.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Capzb
Protein Name capping protein (actin filament) muscle Z-line, beta
Synonyms 1700120C01Rik; AI325129; Cappb1; CPB1; CPB2; CPbeat2; CPbeta1; CPbeta2;
Species Mus musculus
Ensembl Protein ENSMUSP00000114973
InnateDB Gene IDBG-200253 (Capzb)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 38 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0048487 beta-tubulin binding
GO:0051015 actin filament binding
Biological Process
GO:0030030 cell projection organization
GO:0030032 lamellipodium assembly
GO:0030036 actin cytoskeleton organization
GO:0031115 negative regulation of microtubule polymerization
GO:0031175 neuron projection development
GO:0048747 muscle fiber development
GO:0051016 barbed-end actin filament capping
GO:0090036 regulation of protein kinase C signaling
Cellular Component
GO:0001669 acrosomal vesicle
GO:0008290 F-actin capping protein complex
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0030018 Z disc
GO:0030027 lamellipodium
GO:0030863 cortical cytoskeleton
GO:0071203 WASH complex
Protein Structure and Domains
PDB ID MGI:104652
InterPro IPR001698 F-actin-capping protein subunit beta
PFAM PF01115
PRINTS PR00192
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F6YHZ8
UniProt Splice Variant
Entrez Gene 12345
UniGene Mm.408887
RefSeq
MGI ID
MGI Symbol Capzb
OMIM
CCDS
HPRD
IMGT
EMBL AL807811
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca