InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Actc1

Summary

InnateDB Protein

IDBP-534397.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Actc1

Protein Name

actin, alpha, cardiac muscle 1

Synonyms

Actc-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123370

InnateDB Gene

IDBG-197312 (Actc1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0017022	myosin binding

Biological Process

GO:0006200	ATP catabolic process
GO:0030240	skeletal muscle thin filament assembly
GO:0031032	actomyosin structure organization
GO:0033275	actin-myosin filament sliding
GO:0042493	response to drug
GO:0043066	negative regulation of apoptotic process
GO:0045471	response to ethanol
GO:0055003	cardiac myofibril assembly
GO:0055008	cardiac muscle tissue morphogenesis
GO:0060048	cardiac muscle contraction
GO:0070252	actin-mediated cell contraction

Cellular Component

GO:0031674	I band
GO:0042643	actomyosin, actin part
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:87905

InterPro

IPR004000 Actin-related protein

PFAM

PF00022

PRINTS

PR00190

PIRSF

SMART

SM00268

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F6WX90

UniProt Splice Variant

Entrez Gene

11464

UniGene

Mm.686

RefSeq

MGI ID

MGI Symbol

Actc1

OMIM

CCDS

HPRD

IMGT

EMBL

AL844569

GenPept