InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mvp

Summary

InnateDB Protein

IDBP-534540.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mvp

Protein Name

major vault protein

Synonyms

2310009M24Rik; LRP; VAULT1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119213

InnateDB Gene

IDBG-209997 (Mvp)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0019901	protein kinase binding
GO:0019903	protein phosphatase binding

Biological Process

GO:0023057	negative regulation of signaling
GO:0031953	negative regulation of protein autophosphorylation
GO:0038127	ERBB signaling pathway
GO:0061099	negative regulation of protein tyrosine kinase activity

Cellular Component

GO:0005634	nucleus
GO:0005856	cytoskeleton
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1925638

InterPro

IPR002499 Major vault protein, N-terminal

PFAM

PF01505

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z2N7

UniProt Splice Variant

Entrez Gene

78388

UniGene

RefSeq

MGI ID

MGI Symbol

Mvp

OMIM

CCDS

HPRD

IMGT

EMBL

AC122863

GenPept