Mus musculus Protein: Shox2
Summary
InnateDB Protein IDBP-534689.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Shox2
Protein Name short stature homeobox 2
Synonyms 6330543G17Rik; OG12; Og12x; Prx3; SHOT;
Species Mus musculus
Ensembl Protein ENSMUSP00000125031
InnateDB Gene IDBG-149928 (Shox2)
Protein Structure
UniProt Annotation
Function May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation. May also have a role in heart development.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity Highly expressed in striated muscle followed by liver, kidney, testis, brain, heart, lung and spleen.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
Protein Structure and Domains
PDB ID MGI:1201673
InterPro IPR000047 Helix-turn-helix motif
IPR001356 Homeobox domain
IPR003654 OAR domain
IPR009057 Homeodomain-like
PFAM PF00046
PF03826
PRINTS PR00031
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-P70390
TrEMBL
UniProt Splice Variant
Entrez Gene 20429
UniGene Mm.39093
RefSeq
MGI ID
MGI Symbol Shox2
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept