InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dusp15

Summary

InnateDB Protein

IDBP-534745.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dusp15

Protein Name

dual specificity phosphatase-like 15

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123090

InnateDB Gene

IDBG-209929 (Dusp15)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Isoform 2 is highly expressed in testis. {ECO:0000269PubMed:11432789}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0008138	protein tyrosine/serine/threonine phosphatase activity
GO:0016791	phosphatase activity

Biological Process

GO:0006470	protein dephosphorylation
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation
GO:0042127	regulation of cell proliferation
GO:0046330	positive regulation of JNK cascade

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:1934928

InterPro

IPR000340 Dual specificity phosphatase, catalytic domain
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR020417 Atypical dual specificity phosphatase
IPR020422 Dual specificity phosphatase, subgroup, catalytic domain
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00782

PRINTS

PR01908

PIRSF

SMART

SM00195

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt