Version 5.4
Mus musculus Protein: Flna
Summary
InnateDB Protein IDBP-534863.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Flna
Protein Name filamin, alpha
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000116758
InnateDB Gene IDBG-155134 (Flna)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
They are also associated with 119 interaction(s) predicted by orthology.
Experimentally validated
Total 31 [view]
Protein-Protein 31 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 119 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005080 protein kinase C binding
GO:0005515 protein binding
Biological Process
GO:0001837 epithelial to mesenchymal transition
GO:0030036 actin cytoskeleton organization
GO:0045022 early endosome to late endosome transport
GO:0090307 spindle assembly involved in mitosis
Cellular Component
GO:0005802 trans-Golgi network
GO:0031523 Myb complex
Protein Structure and Domains
PDB ID MGI:95556
InterPro IPR001298 Filamin/ABP280 repeat
IPR014756 Immunoglobulin E-set
IPR017868 Filamin/ABP280 repeat-like
PFAM PF00630
PRINTS
PIRSF
SMART SM00557
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J3JS91
UniProt Splice Variant
Entrez Gene 192176
UniGene Mm.295533
RefSeq
MGI ID
MGI Symbol Flna
OMIM
CCDS
HPRD
IMGT
EMBL AL807376
GenPept CAM24325

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca