Version 5.4
| Mus musculus Protein: Cfb | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-535078.4 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Cfb | ||||||||
| Protein Name | complement factor B | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000119977 | ||||||||
| InnateDB Gene | IDBG-488478 (Cfb) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. | ||||||||
| Subcellular Localization | Secreted. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:105975 | ||||||||
| InterPro |
IPR000436
Sushi/SCR/CCP IPR001254 Peptidase S1 IPR001314 Peptidase S1A, chymotrypsin-type IPR002035 von Willebrand factor, type A IPR009003 Trypsin-like cysteine/serine peptidase domain IPR011360 Complement B/C2 |
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| PFAM |
PF00084
PF00089 PF00092 |
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| PRINTS |
PR00722
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| PIRSF |
PIRSF001154
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| SMART |
SM00032
SM00020 SM00327 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P04186 | ||||||||
| PhosphoSite | PhosphoSite-P04186 | ||||||||
| TrEMBL | Q3UEG8 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 14962 | ||||||||
| UniGene | Mm.653 | ||||||||
| RefSeq | XP_006523734 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Cfb | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF049850 AF109906 AK149531 BC005451 CH466666 K01496 K01497 K01498 M57890 M60629 M60630 M60631 M60632 M60633 M60634 M60635 M60636 M60637 M60638 M60639 M60640 M60641 M60642 M60643 M60644 M60645 M60646 | ||||||||
| GenPept | AAA37379 AAA39549 AAA39550 AAA39551 AAA63293 AAC05283 AAC84160 AAH05451 BAE28943 EDL26738 | ||||||||