Version 5.4
Mus musculus Protein: Gabpb2
Summary
InnateDB Protein IDBP-535272.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gabpb2
Protein Name GA repeat binding protein, beta 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000121283
InnateDB Gene IDBG-171867 (Gabpb2)
Protein Structure
UniProt Annotation
Function Transcription factor capable of interacting with purine rich repeats (GA repeats). Must associate with GABP-alpha to bind DNA.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity High levels in thymus, spleen, kidney and intestine.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:95612
InterPro IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P81069
PhosphoSite PhosphoSite-P81069
TrEMBL Q3TQS9
UniProt Splice Variant
Entrez Gene 213054
UniGene Mm.487033
RefSeq NP_084161
MGI ID
MGI Symbol Gabpb2
OMIM
CCDS CCDS17605
HPRD
IMGT
EMBL AK030849 AK141382 AK163329 BC150160 BC150482
GenPept AAI50161 AAI50483 BAC27157 BAE24666 BAE37303

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca