Version 5.4
Homo sapiens Protein: IFNW1
Summary
InnateDB Protein IDBP-53544.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFNW1
Protein Name interferon, omega 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000369578
InnateDB Gene IDBG-53542 (IFNW1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005126 cytokine receptor binding
GO:0005132 type I interferon receptor binding
Biological Process
GO:0002250 adaptive immune response
GO:0002286 T cell activation involved in immune response
GO:0002323 natural killer cell activation involved in immune response
GO:0006952 defense response
GO:0006959 humoral immune response
GO:0007050 cell cycle arrest
GO:0009615 response to virus
GO:0019221 cytokine-mediated signaling pathway
GO:0030183 B cell differentiation
GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein
GO:0042100 B cell proliferation
GO:0043330 response to exogenous dsRNA
GO:0045087 innate immune response
GO:0045343 regulation of MHC class I biosynthetic process
GO:0051607 defense response to virus
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR000471 Interferon alpha/beta/delta
IPR009079 Four-helical cytokine-like, core
PFAM PF00143
PRINTS PR00266
PIRSF
SMART SM00076
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P05000
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 3467
UniGene Hs.73010
RefSeq NP_002168
HUGO HGNC:5448
OMIM 147553
CCDS CCDS6496
HPRD 00944
IMGT
EMBL AL390882 AY780805 BC069095 BC117290 BC117292 CH471071 M11003 U25670 X02669 X58822
GenPept AAA52724 AAA70091 AAH69095 AAI17291 AAI17293 AAV49320 CAA26501 CAA41626 CAH70158 EAW58624

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca