Mus musculus Protein: Pfkfb4
Summary
InnateDB Protein IDBP-535458.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pfkfb4
Protein Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000116001
InnateDB Gene IDBG-200964 (Pfkfb4)
Protein Structure
UniProt Annotation
Function Synthesis and degradation of fructose 2,6-bisphosphate. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003873 6-phosphofructo-2-kinase activity
GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005524 ATP binding
Biological Process
GO:0006000 fructose metabolic process
GO:0006003 fructose 2,6-bisphosphate metabolic process
GO:0016311 dephosphorylation
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2687284
InterPro IPR003094 Fructose-2,6-bisphosphatase
IPR013078 Histidine phosphatase superfamily, clade-1
IPR013079 6-phosphofructo-2-kinase
IPR016260 Bifunctional 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphate 2-phosphatase
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR029033 Histidine phosphatase superfamily
PFAM PF00300
PF01591
PRINTS PR00991
PIRSF PIRSF000709
SMART SM00855
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6DTY7
PhosphoSite PhosphoSite-Q6DTY7
TrEMBL C9VZF1
UniProt Splice Variant
Entrez Gene 270198
UniGene Mm.132391
RefSeq
MGI ID
MGI Symbol Pfkfb4
OMIM
CCDS
HPRD
IMGT
EMBL AK155172 AY646092 AY707862 AY756065 AY756066 AY756067 BC057594 DQ350638 EU571215
GenPept AAH57594 AAT72897 AAU88258 AAV32501 AAV32502 AAV32503 ABC71307 ACC61773 BAE33093