Mus musculus Protein: Afm
Summary
InnateDB Protein IDBP-535515.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Afm
Protein Name afamin
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000117180
InnateDB Gene IDBG-178684 (Afm)
Protein Structure
UniProt Annotation
Function Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient or across the blood-brain barrier (By similarity). {ECO:0000250}.
Subcellular Localization Secreted. Note=Detected in large and small blood vessels throughout the cortex and the striatum.
Disease Associations
Tissue Specificity Detected in brain (at protein level). Expressed in isolated brain capillaries. {ECO:0000269PubMed:19046407}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008431 vitamin E binding
Biological Process
GO:0051180 vitamin transport
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:2429409
InterPro IPR000264 ALB/AFP/VDB
IPR001703 Alpha-fetoprotein
IPR014760 Serum albumin, N-terminal
IPR020858 Serum albumin-like
PFAM PF00273
PRINTS PR00802
PR00803
PIRSF
SMART SM00103
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O89020
PhosphoSite PhosphoSite-O89020
TrEMBL
UniProt Splice Variant
Entrez Gene 280662
UniGene Mm.348786
RefSeq
MGI ID
MGI Symbol Afm
OMIM
CCDS
HPRD
IMGT
EMBL AJ011080 AK143987 BC026681 BC100597
GenPept AAH26681 AAI00598 BAE25647 CAA09471