Version 5.4
Mus musculus Protein: Galnt6
Summary
InnateDB Protein IDBP-535615.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Galnt6
Protein Name UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000124793
InnateDB Gene IDBG-185067 (Galnt6)
Protein Structure
UniProt Annotation
Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. May participate in synthesis of oncofetal fibronectin. Has activity toward Muc1a, Muc2, EA2 and fibronectin peptides (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:1891640
InterPro IPR000772 Ricin B lectin domain
IPR001173 Glycosyltransferase 2-like
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF00652
PF14200
PF00535
PRINTS
PIRSF
SMART SM00458
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C7U7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 207839
UniGene Mm.22969
RefSeq NP_001155240
MGI ID
MGI Symbol Galnt6
OMIM
CCDS CCDS27843
HPRD
IMGT
EMBL AJ133523 AK028506 AK049222 AK155008 AK159721 BC119324 BC119326
GenPept AAI19325 AAI19327 BAC25984 BAC33618 BAE32989 BAE35316 CAB55352

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca