Version 5.4
Mus musculus Protein: Pstk
Summary
InnateDB Protein IDBP-535727.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pstk
Protein Name phosphoseryl-tRNA kinase
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000118636
InnateDB Gene IDBG-210970 (Pstk)
Protein Structure
UniProt Annotation
Function Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. No activity with other tRNAs has been detected.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0001514 selenocysteine incorporation
GO:0016310 phosphorylation
GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:2685945
InterPro IPR013641 Chromatin associated protein KTI12
IPR020028 L-seryl-tRNA(Sec)kinase, eukaryote
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF08433
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BP74
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 214580
UniGene Mm.402895
RefSeq XP_006507620
MGI ID
MGI Symbol Pstk
OMIM
CCDS
HPRD
IMGT
EMBL AK077585 BC110381 BC115503
GenPept AAI10382 AAI15504 BAC36878

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca