Homo sapiens Protein: MAGEB2
Summary
InnateDB Protein IDBP-53574.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAGEB2
Protein Name melanoma antigen family B, 2
Synonyms CT3.2; DAM6; MAGE-XP-2;
Species Homo sapiens
Ensembl Protein ENSP00000368273
InnateDB Gene IDBG-53572 (MAGEB2)
Protein Structure
UniProt Annotation
Function May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. {ECO:0000269PubMed:20864041}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in testis and placenta, and in a significant fraction of tumors of various histologic types.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Protein Structure and Domains
PDB ID
InterPro IPR002190 MAGE protein
IPR021072 Melanoma associated antigen, MAGE, N-terminal
PFAM PF01454
PF12440
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O15479
PhosphoSite PhosphoSite-O15479
TrEMBL
UniProt Splice Variant
Entrez Gene 4113
UniGene Hs.113824
RefSeq NP_002355
HUGO HGNC:6809
OMIM 300098
CCDS CCDS14219
HPRD 02109
IMGT
EMBL AC005185 AF015766 BC026071 U93163
GenPept AAC23617 AAD01565 AAD10635 AAH26071