Version 5.4
Mus musculus Protein: Itpr2
Summary
InnateDB Protein IDBP-535945.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Itpr2
Protein Name inositol 1,4,5-triphosphate receptor 2
Synonyms AI649341; InsP3R-2; InsP3R-5; insP3R2; Ip3r2; Itpr5;
Species Mus musculus
Ensembl Protein ENSMUSP00000121773
InnateDB Gene IDBG-197946 (Itpr2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005262 calcium channel activity
GO:0015278 calcium-release channel activity
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0006816 calcium ion transport
GO:0048016 inositol phosphate-mediated signaling
GO:0070588 calcium ion transmembrane transport
GO:0071361 cellular response to ethanol
Cellular Component
GO:0005737 cytoplasm
GO:0005938 cell cortex
GO:0016020 membrane
GO:0016529 sarcoplasmic reticulum
GO:0043235 receptor complex
Protein Structure and Domains
PDB ID MGI:99418
InterPro IPR000699 RIH (RyR and IP3R Homology) domain
IPR016093 MIR motif
PFAM PF01365
PF02815
PRINTS
PIRSF
SMART SM00472
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B2KF89
UniProt Splice Variant
Entrez Gene 16439
UniGene Mm.7800
RefSeq
MGI ID
MGI Symbol Itpr2
OMIM
CCDS
HPRD
IMGT
EMBL AC129573 AC153574 AC155836 AC158648 AC174928
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca