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InnateDB Protein
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IDBP-535948.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Actr3b
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Protein Name
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ARP3 actin-related protein 3 homolog B (yeast)
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000121629
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InnateDB Gene
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IDBG-143359 (Actr3b)
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Protein Structure
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| Function |
Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
19 [view]
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| PDB ID |
MGI:2661120
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| InterPro |
IPR004000
Actin-related protein
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| PFAM |
PF00022
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| PRINTS |
PR00190
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| PIRSF |
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| SMART |
SM00268
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q641P0
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
242894
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| UniGene |
Mm.452858
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| RefSeq |
XP_006535777
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| MGI ID |
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| MGI Symbol |
Actr3b
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
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| GenPept |
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Version 5.4