InnateDB Protein
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IDBP-536009.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Atf2
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Protein Name
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activating transcription factor 2
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Synonyms
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Atf-2; CRE-BP; Creb2; D130078H02Rik; D18875; mXBP; Tg(Gzma-Klra1)7Wum;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000118560
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InnateDB Gene
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IDBG-180520 (Atf2)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 208 interaction(s) predicted by orthology.
Experimentally validated |
Total |
41
[view]
|
Protein-Protein |
29
[view]
|
Protein-DNA |
12
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
208 [view]
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Molecular Function |
Accession |
GO Term |
GO:0000980
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RNA polymerase II distal enhancer sequence-specific DNA binding
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GO:0001077
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RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
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GO:0001102
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RNA polymerase II activating transcription factor binding
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GO:0003677
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DNA binding
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GO:0003682
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chromatin binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0004402
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histone acetyltransferase activity
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GO:0005515
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protein binding
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GO:0008140
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cAMP response element binding protein binding
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GO:0019901
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protein kinase binding
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GO:0035497
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cAMP response element binding
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GO:0046872
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metal ion binding
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GO:0046982
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protein heterodimerization activity
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Biological Process |
GO:0003151
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outflow tract morphogenesis
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GO:0006970
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response to osmotic stress
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GO:0016573
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histone acetylation
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GO:0031573
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intra-S DNA damage checkpoint
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GO:0032915
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positive regulation of transforming growth factor beta2 production
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GO:0045444
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fat cell differentiation
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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GO:0051091
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positive regulation of sequence-specific DNA binding transcription factor activity
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GO:0060612
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adipose tissue development
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GO:1902110
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positive regulation of mitochondrial membrane permeability involved in apoptotic process
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Cellular Component |
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PDB ID |
MGI:109349
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InterPro |
IPR007087
Zinc finger, C2H2
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PFAM |
PF00096
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-
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TrEMBL |
A2AQF0
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UniProt Splice Variant |
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Entrez Gene |
11909
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UniGene |
Mm.406406
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RefSeq |
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MGI ID |
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MGI Symbol |
Atf2
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AL844581
AL845523
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GenPept |
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