Version 5.4
Mus musculus Protein: Akap5
Summary
InnateDB Protein IDBP-536185.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Akap5
Protein Name A kinase (PRKA) anchor protein 5
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000114495
InnateDB Gene IDBG-150523 (Akap5)
Protein Structure
UniProt Annotation
Function May anchor the PKA kinase to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Note=Associates with lipid rafts. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0008179 adenylate cyclase binding
Biological Process
GO:0006605 protein targeting
GO:0007165 signal transduction
GO:0010739 positive regulation of protein kinase A signaling
GO:0030819 positive regulation of cAMP biosynthetic process
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:2685104
InterPro IPR001573 Protein kinase A anchoring, WSK motif
PFAM PF03832
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt D3YVF0
PhosphoSite PhosphoSite-NP_001094941
TrEMBL
UniProt Splice Variant
Entrez Gene 238276
UniGene Mm.469062
RefSeq NP_001094941
MGI ID
MGI Symbol Akap5
OMIM
CCDS CCDS49092
HPRD
IMGT
EMBL AC120002
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca