InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rab3il1

Summary

InnateDB Protein

IDBP-536198.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rab3il1

Protein Name

RAB3A interacting protein (rabin3)-like 1

Synonyms

1200014K04Rik; AI115013; C76746; Rab3ail1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121449

InnateDB Gene

IDBG-142981 (Rab3il1)

Protein Structure

UniProt Annotation

Function

Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activates RAB8A and RAB8B (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0017112	Rab guanyl-nucleotide exchange factor activity

Biological Process

GO:0015031	protein transport
GO:0032313	regulation of Rab GTPase activity

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:1922010

InterPro

IPR009449 GDPGTP exchange factor Sec2p

PFAM

PF06428

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8VDV3

PhosphoSite

PhosphoSite-Q8VDV3

TrEMBL

D3YZN2

UniProt Splice Variant

Entrez Gene

74760

UniGene

Mm.488681

RefSeq

MGI ID

MGI Symbol

Rab3il1

OMIM

CCDS

CCDS29569

HPRD

IMGT

EMBL

AC134437 AK132764 AK161298 BC020147

GenPept

AAH20147 BAE21345 BAE36305