InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pax8

Summary

InnateDB Protein

IDBP-536338.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pax8

Protein Name

paired box gene 8

Synonyms

Pax-8;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120319

InnateDB Gene

IDBG-142554 (Pax8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0001656	metanephros development
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0009887	organ morphogenesis
GO:0030154	cell differentiation
GO:0030878	thyroid gland development
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex

Protein Structure and Domains

PDB ID

MGI:97492

InterPro

IPR001523 Paired domain
IPR009057 Homeodomain-like

PFAM

PF00292

PRINTS

PR00027

PIRSF

SMART

SM00351

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2AIU8

UniProt Splice Variant

Entrez Gene

18510

UniGene

Mm.2533

RefSeq

MGI ID

MGI Symbol

Pax8

OMIM

CCDS

HPRD

IMGT

EMBL

AL732528

GenPept