Version 5.4
Mus musculus Protein: Prrt2
Summary
InnateDB Protein IDBP-536434.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prrt2
Protein Name proline-rich transmembrane protein 2
Synonyms 1500031I19Rik; AI195361; DSPB3;
Species Mus musculus
Ensembl Protein ENSMUSP00000124520
InnateDB Gene IDBG-210014 (Prrt2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000305PubMed:22632720}.
Disease Associations
Tissue Specificity Expressed in the brain (at protein level). Also highly expressed in spinal cord. Detected at low levels in the heart, lung, kidney and skin. {ECO:0000269PubMed:22101681, ECO:0000269PubMed:22632720}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0009607 response to biotic stimulus
GO:0050884 neuromuscular process controlling posture
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0045202 synapse
Protein Structure and Domains
PDB ID MGI:1916267
InterPro IPR007593 CD225/Dispanin family
PFAM PF04505
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt E9PUL5
PhosphoSite PhosphoSite-NP_001096033
TrEMBL
UniProt Splice Variant
Entrez Gene 69017
UniGene Mm.392047
RefSeq NP_001096033
MGI ID
MGI Symbol Prrt2
OMIM
CCDS CCDS52405
HPRD
IMGT
EMBL AC122863
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca