Version 5.4
Mus musculus Protein: Ecel1
Summary
InnateDB Protein IDBP-536591.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ecel1
Protein Name endothelin converting enzyme-like 1
Synonyms DINE; xce;
Species Mus musculus
Ensembl Protein ENSMUSP00000125096
InnateDB Gene IDBG-177553 (Ecel1)
Protein Structure
UniProt Annotation
Function May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.
Subcellular Localization Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0003016 respiratory system process
GO:0006508 proteolysis
Cellular Component
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID MGI:1343461
InterPro IPR008753 Peptidase M13, N-terminal domain
IPR018497 Peptidase M13, C-terminal domain
PFAM PF05649
PF01431
PRINTS PR00786
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JMI0
PhosphoSite PhosphoSite-Q9JMI0
TrEMBL
UniProt Splice Variant
Entrez Gene 13599
UniGene Mm.140765
RefSeq XP_006529183
MGI ID
MGI Symbol Ecel1
OMIM
CCDS CCDS15128
HPRD
IMGT
EMBL AB026294 BC057569 CH466520
GenPept AAH57569 BAA95005 EDL40189

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca