Version 5.4
| Mus musculus Protein: Gtpbp3 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-536621.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Gtpbp3 | ||||||||
| Protein Name | GTP binding protein 3 | ||||||||
| Synonyms | 2410009F13Rik; AI607903; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000114193 | ||||||||
| InnateDB Gene | IDBG-165806 (Gtpbp3) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. {ECO:0000250}. | ||||||||
| Subcellular Localization | Mitochondrion {ECO:0000269PubMed:14680828}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Ubiquitously expressed. Highly expressed in tissues with high metabolic rates including heart, liver and brain. Weakly expressed in skeletal muscle. {ECO:0000269PubMed:14680828}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1917609 | ||||||||
| InterPro |
IPR004520
tRNA modification GTPase MnmE IPR005225 Small GTP-binding protein domain IPR006073 GTP binding domain IPR011619 Ferrous iron transport protein B, N-terminal IPR018948 GTP-binding protein TrmE, N-terminal IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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| PFAM |
PF01926
PF02421 PF10396 |
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| PRINTS |
PR00326
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q923K4 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | Q8C1M1 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 70359 | ||||||||
| UniGene | Mm.486680 | ||||||||
| RefSeq | XP_006509800 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Gtpbp3 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS40384 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF361482 AK010459 AY029613 BC092042 BC138560 DS033666 | ||||||||
| GenPept | AAH92042 AAI38561 AAK35216 AAK60410 BAC25298 EDL01029 | ||||||||