InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cdk5r2

Summary

InnateDB Protein

IDBP-537127.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cdk5r2

Protein Name

cyclin-dependent kinase 5, regulatory subunit 2 (p39)

Synonyms

B230310J22Rik; p39;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000125322

InnateDB Gene

IDBG-486630 (Cdk5r2)

Protein Structure

UniProt Annotation

Function

Activator of CDK5/TPKII.

Subcellular Localization

Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008092	cytoskeletal protein binding
GO:0008289	lipid binding
GO:0016534	cyclin-dependent protein kinase 5 activator activity

Biological Process

GO:0001764	neuron migration
GO:0021549	cerebellum development
GO:0021722	superior olivary nucleus maturation
GO:0021766	hippocampus development
GO:0021819	layer formation in cerebral cortex
GO:0045860	positive regulation of protein kinase activity
GO:0045956	positive regulation of calcium ion-dependent exocytosis
GO:0071902	positive regulation of protein serine/threonine kinase activity