Version 5.4
Mus musculus Protein: Adad1
Summary
InnateDB Protein IDBP-537151.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adad1
Protein Name adenosine deaminase domain containing 1 (testis specific)
Synonyms Tenr;
Species Mus musculus
Ensembl Protein ENSMUSP00000115260
InnateDB Gene IDBG-140104 (Adad1)
Protein Structure
UniProt Annotation
Function Plays a role in spermatogenesis. Binds to RNA but not to DNA. {ECO:0000269PubMed:15649457}.
Subcellular Localization Nucleus {ECO:0000269PubMed:7543294}.
Disease Associations
Tissue Specificity Testis-specific. Detected in round spermatid cells from stage II-XI (at protein level). Expressed in germ cells from mid-pachytene spermatocytes to mid-round spermatids. {ECO:0000269PubMed:7543294}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004000 adenosine deaminase activity
Biological Process
GO:0006396 RNA processing
GO:0007275 multicellular organismal development
GO:0007286 spermatid development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:103258
InterPro IPR002466 Adenosine deaminase/editase
IPR014720 Double-stranded RNA-binding domain
PFAM PF02137
PF00035
PRINTS
PIRSF
SMART SM00552
SM00358
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SUE7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 21744
UniGene Mm.8122
RefSeq NP_033376
MGI ID
MGI Symbol Adad1
OMIM
CCDS CCDS17315
HPRD
IMGT
EMBL AF195956 AK133008 AL645753 AL645807 AL645966 AL662823 AV255684 BC107346 X84693
GenPept AAF32273 AAI07347 BAE21467 CAA59168 CAI26206 CAM18412 CAM18414 CAM28065 CAM28066 CAM28072 CAM28078

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca