Version 5.4
Mus musculus Protein: Slc47a2
Summary
InnateDB Protein IDBP-537681.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc47a2
Protein Name solute carrier family 47, member 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000120907
InnateDB Gene IDBG-182551 (Slc47a2)
Protein Structure
UniProt Annotation
Function Solute transporter for tetraethylammonium (TEA), cimetidine, choline, procainamide, cimetidine, quinidine, guanidine, N-methylnicotinamide (NMN). Responsible for the secretion of cationic drugs across the brush border membranes. {ECO:0000269PubMed:17715386}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Localized to the plasma membrane and to the intracellular organelles. {ECO:0000269PubMed:17715386}.
Disease Associations
Tissue Specificity Expressed in testis; especially in testicular Leydig cells. {ECO:0000269PubMed:17715386}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0015238 drug transmembrane transporter activity
GO:0015297 antiporter activity
Biological Process
GO:0006855 drug transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:3588190
InterPro IPR002528 Multi antimicrobial extrusion protein
PFAM PF01554
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Z4YMV2
UniProt Splice Variant
Entrez Gene 380701
UniGene Mm.340166
RefSeq
MGI ID
MGI Symbol Slc47a2
OMIM
CCDS
HPRD
IMGT
EMBL AL669884
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca