Version 5.4
Mus musculus Protein: Gsn
Summary
InnateDB Protein IDBP-537984.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gsn
Protein Name gelsolin
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000118120
InnateDB Gene IDBG-164316 (Gsn)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
GO:0007568 aging
GO:0008154 actin polymerization or depolymerization
GO:0014003 oligodendrocyte development
GO:0016192 vesicle-mediated transport
GO:0030155 regulation of cell adhesion
GO:0042246 tissue regeneration
GO:0045471 response to ethanol
GO:0048015 phosphatidylinositol-mediated signaling
GO:0051593 response to folic acid
GO:0060271 cilium morphogenesis
GO:0071276 cellular response to cadmium ion
Cellular Component
GO:0001726 ruffle
GO:0005615 extracellular space
GO:0015629 actin cytoskeleton
GO:0030027 lamellipodium
GO:0043234 protein complex
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:95851
InterPro IPR007122 Villin/Gelsolin
IPR007123 Gelsolin-like domain
PFAM PF00626
PRINTS PR00597
PIRSF
SMART SM00262
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A6PWS5
UniProt Splice Variant
Entrez Gene 227753
UniGene Mm.470521
RefSeq
MGI ID
MGI Symbol Gsn
OMIM
CCDS
HPRD
IMGT
EMBL AL773523
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca