InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GK

Summary

InnateDB Protein

IDBP-53830.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GK

Protein Name

glycerol kinase

Synonyms

GK1; GKD;

Species

Homo sapiens

Ensembl Protein

ENSP00000368229

InnateDB Gene

IDBG-53826 (GK)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004370	glycerol kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016773	phosphotransferase activity, alcohol group as acceptor

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006071	glycerol metabolic process
GO:0006072	glycerol-3-phosphate metabolic process
GO:0006641	triglyceride metabolic process
GO:0016310	phosphorylation
GO:0019432	triglyceride biosynthetic process
GO:0019563	glycerol catabolic process
GO:0044255	cellular lipid metabolic process
GO:0044281	small molecule metabolic process
GO:0046167	glycerol-3-phosphate biosynthetic process

Cellular Component

GO:0005741	mitochondrial outer membrane
GO:0005829	cytosol
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR005999 Glycerol kinase
IPR018484 Carbohydrate kinase, FGGY, N-terminal
IPR018485 Carbohydrate kinase, FGGY, C-terminal

PFAM

PF00370
PF02782

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-P32189

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AC005913 AC112496 AC117404 AJ252550 AJ252551 AJ252552 AJ252553 AJ252554 AJ252555 AJ252556 AJ252557 AJ252558 AJ252559 AJ252560 AJ252561 AJ252562 AJ252563 AJ252564 AJ252565 AJ252566 AJ252567 AJ252568 AJ252569 AJ252570 AK313215 BC037549 BC042421 BC071595 L13943 X68285 X69886 X78211

GenPept

AAA52576 AAH37549 AAH42421 AAH71595 BAG36030 CAA48346 CAA49512 CAB54857 CAB54858 CAB54859

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca