Version 5.4
Mus musculus Protein: Hyal1
Summary
InnateDB Protein IDBP-538348.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hyal1
Protein Name hyaluronoglucosaminidase 1
Synonyms Hya1; Hyal-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000122601
InnateDB Gene IDBG-197764 (Hyal1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004415 hyalurononglucosaminidase activity
GO:0008134 transcription factor binding
GO:0050501 hyaluronan synthase activity
Biological Process
GO:0000302 response to reactive oxygen species
GO:0005975 carbohydrate metabolic process
GO:0006954 inflammatory response
GO:0010634 positive regulation of epithelial cell migration
GO:0030213 hyaluronan biosynthetic process
GO:0030214 hyaluronan catabolic process
GO:0030307 positive regulation of cell growth
GO:0030308 negative regulation of cell growth
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0045766 positive regulation of angiogenesis
GO:0045785 positive regulation of cell adhesion
GO:0046677 response to antibiotic
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051216 cartilage development
GO:0060272 embryonic skeletal joint morphogenesis
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071467 cellular response to pH
GO:0071493 cellular response to UV-B
GO:1900106 positive regulation of hyaluranon cable assembly
Cellular Component
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0031410 cytoplasmic vesicle
GO:0036117 hyaluranon cable
Protein Structure and Domains
PDB ID MGI:96298
InterPro IPR017853 Glycoside hydrolase, superfamily
IPR018155 Hyaluronidase
PFAM PF01630
PRINTS PR00846
PIRSF PIRSF038193
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RFV7
UniProt Splice Variant
Entrez Gene 15586
UniGene Mm.475658
RefSeq
MGI ID
MGI Symbol Hyal1
OMIM
CCDS
HPRD
IMGT
EMBL AL672219
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca