InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Crispld2

Summary

InnateDB Protein

IDBP-538406.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Crispld2

Protein Name

cysteine-rich secretory protein LCCL domain containing 2

Synonyms

1810049K24Rik; coffeecrisp; Lcrisp2; Lgl1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000122962

InnateDB Gene

IDBG-196107 (Crispld2)

Protein Structure

UniProt Annotation

Function

Promotes matrix assembly. {ECO:0000269PubMed:18757743}.

Subcellular Localization

Secreted {ECO:0000269PubMed:18757743}.

Disease Associations

Tissue Specificity

Present in kidney renal tubules (at protein level). {ECO:0000269PubMed:18757743}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005539	glycosaminoglycan binding
GO:0008201	heparin binding

Biological Process

GO:0030198	extracellular matrix organization
GO:0030324	lung development
GO:0060325	face morphogenesis

Cellular Component

GO:0005576	extracellular region
GO:0030133	transport vesicle
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

MGI:1926142

InterPro

IPR001283 Cysteine-rich secretory protein, allergen V5/Tpx-1-related
IPR004043 LCCL domain
IPR014044 CAP domain

PFAM

PF03815
PF00188

PRINTS

PR00837

PIRSF

PIRSF038921

SMART

SM00603
SM00198

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BZQ2

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

78892

UniGene

Mm.402181

RefSeq

NP_084485

MGI ID

MGI Symbol

Crispld2

OMIM

CCDS

CCDS22714

HPRD

IMGT

EMBL

AK019034 AK033858 AK154308 BC090642 CH466525

GenPept

AAH90642 BAB31519 BAC28498 BAE32505 EDL11621 EDL11622