InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pif1

Summary

InnateDB Protein

IDBP-538462.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pif1

Protein Name

PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120400

InnateDB Gene

IDBG-178111 (Pif1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0005524	ATP binding
GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity
GO:0033682	ATP-dependent 5'-3' DNA/RNA helicase activity
GO:0042162	telomeric DNA binding
GO:0043141	ATP-dependent 5'-3' DNA helicase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0032204	regulation of telomere maintenance
GO:0032508	DNA duplex unwinding
GO:0051974	negative regulation of telomerase activity

Cellular Component

GO:0000784

nuclear chromosome, telomeric region

Protein Structure and Domains

PDB ID

MGI:2143057

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3YZ87

UniProt Splice Variant

Entrez Gene

208084

UniGene

Mm.396612

RefSeq

MGI ID

MGI Symbol

Pif1

OMIM

CCDS

HPRD

IMGT

EMBL

AC135108

GenPept