InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ruvbl2

Summary

InnateDB Protein

IDBP-538619.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ruvbl2

Protein Name

RuvB-like protein 2

Synonyms

mp47; p47;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118973

InnateDB Gene

IDBG-182997 (Ruvbl2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 195 interaction(s) predicted by orthology.

Experimentally validated
Total	24 [view]
Protein-Protein	24 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	195 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003678	DNA helicase activity
GO:0003684	damaged DNA binding
GO:0005524	ATP binding
GO:0042802	identical protein binding
GO:0043141	ATP-dependent 5'-3' DNA helicase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006260	DNA replication
GO:0006281	DNA repair
GO:0032508	DNA duplex unwinding
GO:0034644	cellular response to UV
GO:0043967	histone H4 acetylation
GO:0043968	histone H2A acetylation

Cellular Component

GO:0030529	ribonucleoprotein complex
GO:0031011	Ino80 complex
GO:0035267	NuA4 histone acetyltransferase complex
GO:0071339	MLL1 complex

Protein Structure and Domains

PDB ID

MGI:1342299

InterPro

IPR003959 ATPase, AAA-type, core
IPR004504 DNA repair protein RadA
IPR007694 DNA helicase, DnaB-like, C-terminal
IPR010339 TIP49, C-terminal
IPR012340 Nucleic acid-binding, OB-fold
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00004
PF07724
PF13304
PF03796
PF06068

PRINTS

PR01874

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite