Version 5.4
Mus musculus Protein: Tnni2
Summary
InnateDB Protein IDBP-538648.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tnni2
Protein Name troponin I, skeletal, fast 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000122733
InnateDB Gene IDBG-212558 (Tnni2)
Protein Structure
UniProt Annotation
Function Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0031014 troponin T binding
GO:0046872 metal ion binding
Biological Process
GO:0003009 skeletal muscle contraction
GO:0006937 regulation of muscle contraction
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005861 troponin complex
Protein Structure and Domains
PDB ID MGI:105070
InterPro IPR001978 Troponin
PFAM PF00992
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P13412
PhosphoSite PhosphoSite-P13412
TrEMBL A2A6K0
UniProt Splice Variant
Entrez Gene 21953
UniGene
RefSeq
MGI ID
MGI Symbol Tnni2
OMIM
CCDS CCDS40192
HPRD
IMGT
EMBL AL603651 BC028515 J04992
GenPept AAA40485 AAH28515 CAM23286

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca