InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ttn

Summary

InnateDB Protein

IDBP-538649.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ttn

Protein Name

titin

Synonyms

1100001C23Rik; 2310036G12Rik; 2310057K23Rik; 2310074I15Rik; AF006999; AV006427; D330041I19Rik; D830007G01Rik; L56; mdm; shru;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117447

InnateDB Gene

IDBG-182351 (Ttn)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 95 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	95 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005200	structural constituent of cytoskeleton
GO:0005515	protein binding

Biological Process

GO:0001701	in utero embryonic development
GO:0003007	heart morphogenesis
GO:0006936	muscle contraction
GO:0007512	adult heart development
GO:0043056	forward locomotion
GO:0045214	sarcomere organization
GO:0055002	striated muscle cell development
GO:0055003	cardiac myofibril assembly

Cellular Component

GO:0005859	muscle myosin complex
GO:0030017	sarcomere
GO:0030018	Z disc
GO:0031430	M band
GO:0031672	A band
GO:0031674	I band

Protein Structure and Domains

PDB ID

MGI:98864

InterPro

IPR003596 Immunoglobulin V-set, subgroup
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF07679
PF07686
PF00047

PRINTS

PIRSF

SMART

SM00406
SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q8R4N3

UniProt Splice Variant

Entrez Gene

22138

UniGene

Mm.473358

RefSeq

MGI ID

MGI Symbol

Ttn

OMIM

CCDS

HPRD

IMGT

EMBL

AF426841 AF426843 AL928681 AL928721 AL928789

GenPept

AAL84321 AAL84322