Mus musculus Protein: Bahd1
Summary
InnateDB Protein IDBP-538730.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bahd1
Protein Name bromo adjacent homology domain containing 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000118998
InnateDB Gene IDBG-198718 (Bahd1)
Protein Structure
UniProt Annotation
Function Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains. May act by recruiting heterochromatin proteins such as CBX5 (HP1 alpha), HDAC5 and MBD1. Represses IGF2 expression by binding to its CpG-rich P3 promoter and recruiting heterochromatin proteins (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus. Chromosome. Note=Localizes to heterochromatin and inactive X chromosome. Colocalizes with histone H3 trimethylated at 'Lys-27' (H3K27me3) (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Protein Structure and Domains
PDB ID MGI:2139371
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q497V6
TrEMBL Z4YMJ8
UniProt Splice Variant
Entrez Gene 228536
UniGene Mm.462543
RefSeq
MGI ID
MGI Symbol Bahd1
OMIM
CCDS
HPRD
IMGT
EMBL AL772255 AL845164
GenPept