InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cul1

Summary

InnateDB Protein

IDBP-538752.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cul1

Protein Name

cullin 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000122702

InnateDB Gene

IDBG-143474 (Cul1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 599 interaction(s) predicted by orthology.

Experimentally validated
Total	38 [view]
Protein-Protein	38 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	599 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0031625	ubiquitin protein ligase binding

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0006513	protein monoubiquitination
GO:0006915	apoptotic process
GO:0008283	cell proliferation
GO:0009887	organ morphogenesis

Cellular Component

GO:0019005	SCF ubiquitin ligase complex
GO:0031461	cullin-RING ubiquitin ligase complex

Protein Structure and Domains

PDB ID

MGI:1349658

InterPro

IPR001373 Cullin, N-terminal
IPR016158 Cullin homology
IPR016159 Cullin repeat-like-containing domain

PFAM

PF00888

PRINTS

PIRSF

SMART

SM00182

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3TPM3

UniProt Splice Variant

Entrez Gene

26965

UniGene

Mm.87611

RefSeq

MGI ID

MGI Symbol

Cul1

OMIM

CCDS

HPRD

IMGT

EMBL

AC154014 AC154015 AK164274

GenPept

BAE37713