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InnateDB Protein
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IDBP-538906.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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B3gat1
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Protein Name
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beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
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Synonyms
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0710007K08Rik; AI846286; GlcAT-P; Glcatp; Hnk1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000124752
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InnateDB Gene
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IDBG-145008 (B3gat1)
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Protein Structure
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| Function |
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
1 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0008499
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UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
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GO:0015018
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galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
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GO:0015020
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glucuronosyltransferase activity
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GO:0046872
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metal ion binding
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| Biological Process |
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| Cellular Component |
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| PDB ID |
MGI:1924148
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| InterPro |
IPR005027
Glycosyl transferase, family 43
IPR029044
Nucleotide-diphospho-sugar transferases
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| PFAM |
PF03360
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q9CW73
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
76898
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| UniGene |
Mm.488293
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
B3gat1
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AK003020
AK044599
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| GenPept |
BAB22514
BAC31996
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Version 5.4