InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Katnal2

Summary

InnateDB Protein

IDBP-538927.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Katnal2

Protein Name

katanin p60 subunit A-like 2

Synonyms

3110023G01Rik; 4933439B08Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119066

InnateDB Gene

IDBG-159438 (Katnal2)

Protein Structure

UniProt Annotation

Function

Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. {ECO:0000255HAMAP-Rule:MF_03025}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000255HAMAP- Rule:MF_03025}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding
GO:0008568	microtubule-severing ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0008150	biological_process
GO:0051013	microtubule severing

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm
GO:0005874	microtubule

Protein Structure and Domains

PDB ID

MGI:1924234

InterPro

IPR006594 LisH dimerisation motif
IPR013720 LisH dimerisation motif, subgroup

PFAM

PF08513

PRINTS

PIRSF

SMART

SM00667

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D3R6

PhosphoSite

PhosphoSite-Q9D3R6

TrEMBL

UniProt Splice Variant

Entrez Gene

71206

UniGene

Mm.489832

RefSeq

MGI ID

MGI Symbol

Katnal2

OMIM

CCDS

HPRD

IMGT

EMBL

AC132608 AK017114 BC069977

GenPept

AAH69977 BAB30604