Version 5.4
Mus musculus Protein: Lyrm7
Summary
InnateDB Protein IDBP-539255.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lyrm7
Protein Name LYR motif containing 7
Synonyms 1700024C24Rik; 9330147L21Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000120778
InnateDB Gene IDBG-174112 (Lyrm7)
Protein Structure
UniProt Annotation
Function Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion matrix {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Protein Structure and Domains
PDB ID MGI:1922780
InterPro IPR008011 Complex 1 LYR protein
PFAM PF05347
PF13232
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DA03
PhosphoSite PhosphoSite-Q9DA03
TrEMBL B9EIE8
UniProt Splice Variant
Entrez Gene 75530
UniGene Mm.83578
RefSeq NP_083603
MGI ID
MGI Symbol Lyrm7
OMIM
CCDS CCDS36154
HPRD
IMGT
EMBL AK006294 AL954817 BC139403 BC139406
GenPept AAI39404 AAI39407 BAB24512 CAX15806

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca