Version 5.4
Mus musculus Protein: Echdc1
Summary
InnateDB Protein IDBP-539370.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Echdc1
Protein Name enoyl Coenzyme A hydratase domain containing 1
Synonyms 1700028A24Rik; AI314462; AI930038; D10Ertd667e; MMCD;
Species Mus musculus
Ensembl Protein ENSMUSP00000125553
InnateDB Gene IDBG-141831 (Echdc1)
Protein Structure
UniProt Annotation
Function Decarboxylases ethylmalonyl-CoA decarboxylase, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level. {ECO:0000269PubMed:22016388}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000305PubMed:22016388}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004492 methylmalonyl-CoA decarboxylase activity
GO:0016831 carboxy-lyase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:1277169
InterPro IPR001753 Crotonase superfamily
IPR029045 ClpP/crotonase-like domain
PFAM PF00378
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D9V3
PhosphoSite PhosphoSite-Q9D9V3
TrEMBL E0CXS3
UniProt Splice Variant
Entrez Gene 52665
UniGene Mm.405984
RefSeq NP_001103665
MGI ID
MGI Symbol Echdc1
OMIM
CCDS CCDS48528
HPRD
IMGT
EMBL AC153912 AK003965 AK006444 AK028775 AK145162 AK150932 AK152285 AK153454 AK166589 AK166634 AK166660 BC066183
GenPept AAH66183 BAB23096 BAB24592 BAC26112 BAE26268 BAE29969 BAE31098 BAE32007 BAE38876 BAE38907 BAE38924

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca