InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Parp4

Summary

InnateDB Protein

IDBP-539444.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Parp4

Protein Name

poly (ADP-ribose) polymerase family, member 4

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000124258

InnateDB Gene

IDBG-167551 (Parp4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003950	NAD+ ADP-ribosyltransferase activity
GO:0005515	protein binding
GO:0019899	enzyme binding

Biological Process

GO:0006464	cellular protein modification process
GO:0006471	protein ADP-ribosylation
GO:0006954	inflammatory response
GO:0008219	cell death

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005819	spindle
GO:0005876	spindle microtubule
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:2685589

InterPro

IPR001357 BRCT domain
IPR002035 von Willebrand factor, type A
IPR004102 Poly(ADP-ribose) polymerase, regulatory domain
IPR009408 Formin Homology 1
IPR012317 Poly(ADP-ribose) polymerase, catalytic domain
IPR013694 VIT domain

PFAM