InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pigyl

Summary

InnateDB Protein

IDBP-539453.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pigyl

Protein Name

phosphatidylinositol glycan anchor biosynthesis, class Y-like

Synonyms

1810008A14Rik; PIG-Y; Pigy;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000116929

InnateDB Gene

IDBG-143445 (Pigyl)

Protein Structure

UniProt Annotation

Function

Component of the GPI-GlcNAc transferase (GPI-GnT) complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI- anchors for cell surface proteins. May act by regulating the catalytic subunit PIGA (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0006506	GPI anchor biosynthetic process
GO:0008150	biological_process

Cellular Component

GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0005575	cellular_component
GO:0005789	endoplasmic reticulum membrane
GO:0005886	plasma membrane
GO:0016021	integral component of membrane