InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Trim32

Summary

InnateDB Protein

IDBP-539749.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Trim32

Protein Name

tripartite motif-containing 32

Synonyms

1810045E12Rik; 3f3; BBS11; Zfp117;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121949

InnateDB Gene

IDBG-156706 (Trim32)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	44 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0017022	myosin binding
GO:0031369	translation initiation factor binding
GO:0043130	ubiquitin binding
GO:0043621	protein self-association
GO:0046872	metal ion binding

Biological Process

GO:0000209	protein polyubiquitination
GO:0016567	protein ubiquitination
GO:0030307	positive regulation of cell growth
GO:0030335	positive regulation of cell migration
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045087	innate immune response (InnateDB)
GO:0045732	positive regulation of protein catabolic process
GO:0045787	positive regulation of cell cycle
GO:0045862	positive regulation of proteolysis
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005863	striated muscle myosin thick filament

Protein Structure and Domains

PDB ID

MGI:1917057

InterPro

IPR000315 Zinc finger, B-box
IPR001841 Zinc finger, RING-type
IPR018957 Zinc finger, C3HC4 RING-type

PFAM

PF00643
PF13639
PF14634
PF00097

PRINTS

PIRSF

SMART

SM00336
SM00184

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2AGS1

UniProt Splice Variant

Entrez Gene

69807

UniGene

Mm.22786

RefSeq

MGI ID

MGI Symbol

Trim32

OMIM

CCDS

HPRD

IMGT

EMBL

AL691456

GenPept