InnateDB Protein
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IDBP-539894.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Dhcr7
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Protein Name
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7-dehydrocholesterol reductase
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Synonyms
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AA409147;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000121782
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InnateDB Gene
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IDBG-212845 (Dhcr7)
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Protein Structure
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Function |
Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).
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Subcellular Localization |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
8 [view]
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Molecular Function |
Accession |
GO Term |
GO:0047598
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7-dehydrocholesterol reductase activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1298378
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InterPro |
IPR001171
Ergosterol biosynthesis ERG4/ERG24
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PFAM |
PF01222
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O88455
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PhosphoSite |
PhosphoSite-O88455
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TrEMBL |
D3Z7G1
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UniProt Splice Variant |
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Entrez Gene |
13360
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UniGene |
Mm.249342
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RefSeq |
XP_006508539
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MGI ID |
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MGI Symbol |
Dhcr7
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OMIM |
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CCDS |
CCDS22048
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HPRD |
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IMGT |
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EMBL |
AC133502
AF057368
BC006854
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GenPept |
AAC40164
AAH06854
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