Mus musculus Protein: Samd4 | |||||||||
---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||
InnateDB Protein | IDBP-539905.3 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Samd4 | ||||||||
Protein Name | sterile alpha motif domain containing 4 | ||||||||
Synonyms | 1700024G08Rik; 1700111L17Rik; 4933436G17Rik; Samd4a; Smaug; Smaug1; | ||||||||
Species | Mus musculus | ||||||||
Ensembl Protein | ENSMUSP00000114621 | ||||||||
InnateDB Gene | IDBG-153990 (Samd4) | ||||||||
Protein Structure | |||||||||
UniProt Annotation | |||||||||
Function | Acts as a translational repressor of SRE-containing messengers. {ECO:0000250}. | ||||||||
Subcellular Localization | Cytoplasm {ECO:0000269PubMed:16221671}. Cell projection, dendrite {ECO:0000269PubMed:16221671}. Cell junction, synapse, synaptosome {ECO:0000269PubMed:16221671}. Note=Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1. Shuttles between the nucleus and the cytoplasm in a CRM1- dependent manner (By similarity). Enriched in synaptoneurosomes. {ECO:0000250}. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | Expressed in brain (at protein level). {ECO:0000269PubMed:16221671}. | ||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|
||||||||
Gene Ontology | |||||||||
Molecular Function |
|
||||||||
Biological Process |
|
||||||||
Cellular Component |
|
||||||||
Protein Structure and Domains | |||||||||
PDB ID | MGI:1921730 | ||||||||
InterPro |
IPR001660
Sterile alpha motif domain IPR011510 Sterile alpha motif, type 2 IPR013761 Sterile alpha motif/pointed domain IPR021129 Sterile alpha motif, type 1 |
||||||||
PFAM |
PF07647
PF00536 |
||||||||
PRINTS | |||||||||
PIRSF | |||||||||
SMART |
SM00454
|
||||||||
TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | Q8CBY1 | ||||||||
PhosphoSite | PhosphoSite-Q8CBY1 | ||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 74480 | ||||||||
UniGene | Mm.397141 | ||||||||
RefSeq | |||||||||
MGI ID | |||||||||
MGI Symbol | Samd4 | ||||||||
OMIM | |||||||||
CCDS | CCDS26983 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | AC131586 AC159006 AK017081 AK034323 AK134243 AK161277 AK163751 BC049740 BC145827 BC145829 CH466605 DQ278487 | ||||||||
GenPept | AAH49740 AAI45828 AAI45830 ABB83932 BAB30585 BAC28674 BAE22061 BAE36288 BAE37479 EDL20734 | ||||||||