Version 5.4
Mus musculus Protein: Flad1
Summary
InnateDB Protein IDBP-540056.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Flad1
Protein Name RFad1, flavin adenine dinucleotide synthetase, homolog (yeast)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000122252
InnateDB Gene IDBG-164410 (Flad1)
Protein Structure
UniProt Annotation
Function Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003919 FMN adenylyltransferase activity
GO:0005524 ATP binding
Biological Process
GO:0006747 FAD biosynthetic process
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0008152 metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2443030
InterPro IPR001453 Molybdopterin binding domain
IPR002500 Phosphoadenosine phosphosulphate reductase
IPR012183 FAD synthetase, molybdopterin binding
PFAM PF00994
PF01507
PRINTS
PIRSF PIRSF036620
SMART SM00852
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R123
PhosphoSite PhosphoSite-Q8R123
TrEMBL F8WGX4
UniProt Splice Variant
Entrez Gene 319945
UniGene Mm.468543
RefSeq
MGI ID
MGI Symbol Flad1
OMIM
CCDS CCDS38492
HPRD
IMGT
EMBL AC171273 AK044501 AK161929 BC009152 BC025817 BC046769
GenPept AAH09152 AAH25817 AAH46769 BAC31952 BAE36639

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca